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Differential diagnosis generator

Produce a structured differential for a presentation.

PromptDoc Clinical Team Use case: Broadening a differential during workup.

prompt.txt
For a patient presenting with [PRESENTING COMPLAINT], generate a structured differential diagnosis. Group by likelihood (most likely / important to exclude / less likely). For each, give one line of supporting and one line of opposing features. Then list the key investigations that would discriminate between them. This is decision support, not a diagnosis.

Clinical features:
[PASTE FEATURES]

No patient-identifiable information. This is educational decision support only and must not replace clinical judgement.

Example input

Presenting complaint: acute pleuritic chest pain. Features: 32yo, sudden onset, worse on inspiration, mild dyspnoea, recent long-haul flight, HR 102.

Example output

Most likely: pulmonary embolism (supporting: pleuritic pain, tachycardia, recent flight; opposing: no haemoptysis)… Important to exclude: pneumothorax… Discriminating investigations: D-dimer/CTPA, CXR, ECG…

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